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Saccharin

Saccharin, the oldest artificial sweetener, was accidentally discovered in 1879 by researcher Constantine Fahlberg, who was working at Johns Hopkins University in the laboratory of professor Ira Remsen. Fahlberg's discovery came after he forgot to wash his hands before lunch. He had spilled a chemical on his hands and it, in turn, caused the bread he ate to taste unusually sweet. In 1880, the two scientists jointly published the discovery, but in 1884, Fahlberg obtained a patent and began mass-producing saccharin without Remsen. The use of saccharin did not become widespread until sugar was rationed during World War I, and its popularity increased during the 1960s and 1970s with the manufacture of Sweet'N Low and diet soft drinks.

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