Can head trauma really cause amnesia?

If someone has anterograde amnesia, he or she can't remember incidents that happen after the onset of amnesia. A less common device in television or movie scripts, this form of amnesia is central to the plot of the movie "Memento." The main character receives a severe blow to the head and suffers brain damage. Similar to other victims of anterograde amnesia, he can no longer form new memories.

As an amnesiac recovers, he or she usually recalls older memories first, and then more recent memories, until almost all memory is recovered. Memories of events that occurred around the time of the head trauma or onset of amnesia are sometimes never recovered.

When people talk about memory, they're usually thinking about long-term memory. People actually have several different types of memory. The three most important types to consider when thinking about amnesia are:

In order to understand how the loss of memory works, knowing how we store memories in the first place is helpful. The human brain is a truly amazing organ. It gives us the power to think, plan, speak and imagine. It also gives us the ability to make and store memories. Physiologically speaking, a memory is the result of chemical or even structural changes in synaptic transmissions between neurons. As these changes occur, a pathway is created. This pathway is called a memory trace. Signals can travel along these memory traces through the brain.

­

Making and storing memories is a complex process. It involves many regions of the brain, including the frontal, temporal and parietal lobes. Damage or disease in these areas can result in varying degrees of memory loss.

Here's a good example of how memory loss can happen. For short-term memory to become long-term memory, it must go through a process known as consolidation. During consolidation, short-term memory is repeatedly activated - so much so that certain chemical and physical changes occur in the brain, permanently embedding the memory for long-term access. If, during this repeated activation, something interrupts the process - let's say a concussion or other brain trauma - then short-term memory cannot be consolidated. Memories can't be stored for long-term access. This may be what is going on in anterograde amnesia.

It is believed ­that consolidation takes place in the hippocampi, parts of the brain that are located in the temporal-lobe region of the brain. Medical research indicates that it is the frontal and temporal lobes that are most often damaged during head injury. This is why many people who suffer severe head trauma or brain injury experience anterograde amnesia. If the hippocampi are damaged, the amnesiac will be able to recall older memories, but won't be able to make any new ones.

So, yes, it is possible to suffer memory loss - amnesia - as the result of a blow to the head. But, the head trauma must be severe. For a bonk on the head to result in amnesia, the bonk would have to be so incredibly hard that it would cause severe swelling around the temporal lobe and/or injury to this region of the brain. Obviously, another blow to the head would merely result in more head trauma and would most likely exacerbate the problem!