Astronaut Story Musgrave on Earth (left) and in orbit (right). You can see the puffiness around his eyes and cheeks caused by microgravity.

Photos courtesy NASA

How You Feel in Microgravity

When you first encounter microgravity, you have the following feelings:

  • Nausea
  • Disorientation
  • Headache
  • Loss of appetite
  • Congestion

The longer you stay in microgravity, the more your muscles and bones weaken.

These sensations are caused by changes in various systems of your body. Let's take a closer look at how your body responds.

Spacesick

The nausea and disorientation that you feel are like that sinking feeling in your stomach when your car hits a dip in the road or you experience a drop on a roller coaster ride, only you have that feeling constantly for several days. This is the feeling of space sickness, or space motion sickness, which is caused by conflicting information that your brain receives from your eyes and the vestibular organs located in your inner ear. Your eyes can see which way is up and down inside the shuttle. However, because your vestibular system relies on the downward pull of gravity to tell you which way is up versus down and in which direction you are moving, it does not function in microgravity. So your eyes may tell your brain that you are upside-down, but your brain does not receive any interpretable input from your vestibular organs. Your confused brain produces the nausea and disorientation, which in turn may lead to vomiting and loss of appetite. Fortunately, after a few days, your brain adapts to the situation by relying solely on the visual inputs, and you begin to feel better. NASA has issued medication patches to help astronauts deal with the nausea until their bodies adapt.

Puffy Face and Bird Legs

In microgravity, your face will feel full and your sinuses will feel congested, which may contribute to headaches as well as space motion sickness. You feel the same way on Earth when you bend over or stand upside down, because blood rushes to your head.

Shifts in your blood and bodily fluids upon exposure to micro-gravity

On Earth, gravity pulls on your blood, causing significant volumes to pool in the veins of your legs. Once you encounter microgravity, the blood shifts from your legs into your chest and head. Your face tends to get puffy and your sinuses swell, as shown below. The fluid shift also shrinks the size of your legs.

When the blood shifts to the chest, your heart increases in size and pumps more blood with each beat. Your kidneys respond to this increased blood flow by producing more urine, much like they do after you drink a large glass of water. Also, the increase in blood and fluid decreases anti-diuretic hormone (ADH) secretion by the pituitary gland, which makes you less thirsty. Therefore, you do not drink as much water as you might on Earth. Overall, these two factors combine to help rid your chest and head of the excess fluid, and in a few days, your body's fluid levels are less than what they were on Earth. Although you still have a slightly puffy head and stuffy sinuses, it is not as bad after the first couple of days. Upon your return to Earth, gravity will pull those fluids back down to your legs and away from your head, which will cause you to feel faint when you stand up. But you will also begin to drink more, and your fluid levels will return to normal in a couple of days.

Space Anemia

As your kidneys eliminate the excess fluid, they also decrease their secretion of erythropoietin, a hormone that stimulates red blood-cell production by bone marrow cells. The decrease in red blood-cell production matches the decrease in plasma volume so that the hematocrit (percentage of blood volume occupied by red blood cells) is the same as on Earth. Upon your return to Earth, your erythropoietin levels will increase, as will your red blood-cell count.

Weak Muscles

When you are in microgravity, your body adopts a "fetal" posture -- you crouch slightly, with your arms and legs half-bent in front of you. In this position, you do not use many of your muscles, particularly those muscles that help you stand and maintain posture (anti-gravity muscles). As your stay aboard the International Space Station lengthens, your muscles change. The mass of your muscles decreases, which contributes to the "bird leg" appearance. The muscle fiber types change from slow-twitch to fast-twitch. Your body no longer needs slow-twitch endurance fibers, such as those used in standing. Instead, more fast-twitch fibers are needed as you push yourself quickly off of space station surfaces. The longer you stay on the station, the less muscle mass you will have. This loss of muscle mass makes you weaker, presenting problems for long-duration space flights and upon returning home to Earth's gravity.

Brittle Bones

On Earth, your bones support the weight of your body. The size and mass of your bones are balanced by the rates at which certain bone cells (osteoblasts) lay down new mineral layers and other cells (osteoclasts) chew up those mineral layers. In microgravity, your bones do not need to support your body, so all of your bones, especially the weight-bearing bones in your hips, thighs and lower back, are used much less than they are on Earth. In these bones, the rate at which your osteoblasts deposit new bone layers is reduced (no one knows exactly why, though it is thought that changes in force and stress are somehow involved), while the rate at which osteoclasts chew up bone stays the same. The result is that the size and mass of these bones continue to decrease as long as you remain in microgravity, at a rate of approximately 1 percent per month. These changes in bone mass make your bones weak and more likely to break upon your return to Earth's gravity. It is not known how much of the bone loss is recoverable upon return to Earth, although it is probably not 100 percent. These changes in bones may limit the duration of space flights. More research is needed in this area.

In addition to weak bones, your blood's calcium concentration increases slightly as your bones get chewed up by osteoclasts. Your kidneys must get rid of the excess calcium, which makes them susceptible to forming painful kidney stones.